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Structural basis for cooperative RNA binding and export complex assembly by HIV Rev

HIV replication requires nuclear export of unspliced viral RNAs to translate structural proteins and package genomic RNA. Export is mediated by cooperative binding of the Rev protein to the Rev response element (RRE) RNA, forming a highly specific oligomeric ribonucleoprotein (RNP) that binds to the...

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Detalhes bibliográficos
Main Authors: Daugherty, Matthew D., Liu, Bella, Frankel, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988976/
https://ncbi.nlm.nih.gov/pubmed/20953181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1902
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