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Double Strand Break DNA Repair occurs via Non-Homologous End-Joining in Mouse MII Oocytes

The unique biology of the oocyte means that accepted paradigms for DNA repair and protection are not of direct relevance to the female gamete. Instead, preservation of the integrity of the maternal genome depends on endogenous protein stores and/or mRNA transcripts accumulated during oogenesis. The...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Martin, Jacinta H., Bromfield, Elizabeth G., Aitken, R. John, Lord, Tessa, Nixon, Brett
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018751/
https://ncbi.nlm.nih.gov/pubmed/29946146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27892-2
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