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Pharmacokinetic–Pharmacodynamic Model for the Testosterone-Suppressive Effect of Leuprolide in Normal and Prostate Cancer Rats

This study developed the pharmacokinetic (PK)–pharmacodynamic (PD) model of the testosterone-suppressive effect of leuprolide for evaluation of the sustained release (SR) depot and leuprolide solution in rats with or without prostate cancer. Six groups of rats were divided by the routes of administr...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Lee, Dong-Seok, Kim, Sook-Jin, Choi, Go-Wun, Lee, Yong-Bok, Cho, Hea-Young
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017563/
https://ncbi.nlm.nih.gov/pubmed/29662027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040909
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