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Pharmacokinetic–Pharmacodynamic Model for the Testosterone-Suppressive Effect of Leuprolide in Normal and Prostate Cancer Rats

This study developed the pharmacokinetic (PK)–pharmacodynamic (PD) model of the testosterone-suppressive effect of leuprolide for evaluation of the sustained release (SR) depot and leuprolide solution in rats with or without prostate cancer. Six groups of rats were divided by the routes of administr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijät: Lee, Dong-Seok, Kim, Sook-Jin, Choi, Go-Wun, Lee, Yong-Bok, Cho, Hea-Young
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017563/
https://ncbi.nlm.nih.gov/pubmed/29662027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23040909
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