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A Sample and Sensitive HPLC-MS/MS Method for Simultaneous Determination of Ziyuglycoside I and Its Metabolite Ziyuglycoside II in Rat Pharmacokinetics

Ziyuglycoside I (ZGS1) is a promising drug candidate for the treatment of leucopenia. Currently, information on ZGS1 and its in vivo metabolite ziyuglycoside II (ZGS2) is limited. The objective of this study was to investigate the pharmacokinetics, tissue distribution, and excretion of ziyuglycoside...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Li, Zhi-Feng, Zhou, Meng-Ying, Tan, Ting, Zhong, Chen-Cong, Wang, Qi, Pan, Ling-Ling, Luo, Ying-Ying, Yang, Shi-Lin, Feng, Yu-Lin, Ouyang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6017276/
https://ncbi.nlm.nih.gov/pubmed/29495641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23030543
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