Simultaneous quantitation of folic acid and 5-methyltetrahydrofolic acid in human plasma by HPLC–MS/MS and its application to a pharmacokinetic study()

A sensitive method based on high-performance liquid chromatography–tandem mass spectrometry (LC–MS/MS) has been developed for the simultaneous determination of folic acid (FA) and its active metabolite, 5-methyltetrahydrofolic acid (5-M-THF), in human plasma. The analytes were extracted from plasma...

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Vydáno v:J Pharm Anal
Hlavní autoři: Zheng, Xiao-Hong, Jiang, Li-Yuan, Zhao, Lan-Ting, Zhang, Quan-Ying, Ding, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Xi'an Jiaotong University 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762215/
https://ncbi.nlm.nih.gov/pubmed/29403940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2015.05.004
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