Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness

BACKGROUND: Critically ill patients with sepsis and acute respiratory distress syndrome have severely altered physiology and immune system modifications. RNA splicing is a basic molecular mechanism influenced by physiologic alterations. Immune checkpoint inhibitors, such as B and T Lymphocyte Attenu...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Monaghan, Sean F., Banerjee, Debasree, Chung, Chun-Shiang, Lomas-Neira, Joanne, Cygan, Kamil J., Rhine, Christy L., Fairbrother, William G., Heffernan, Daithi S., Levy, Mitchell M., Cioffi, William G., Ayala, Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016894/
https://ncbi.nlm.nih.gov/pubmed/30134817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-018-0036-3
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