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Blockade of Endothelial Growth Factor, Angiopoietin-2, Reduces Indices of ARDS and Mortality in Mice Resulting from the Dual-Insults of Hemorrhagic Shock and Sepsis

We have demonstrated hemorrhagic shock “priming” for the development of indirect (i)ARDS in mice following subsequent septic challenge and show pathology characteristic of patients with iARDS, including increased lung micro-vascular permeability and arterial PO(2)/FI0(2) reduced to levels comparable...

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Foilsithe in:Shock
Main Authors: Lomas-Neira, Joanne L., Heffernan, Daithi S., Ayala, Alfred, Monaghan, Sean F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715730/
https://ncbi.nlm.nih.gov/pubmed/26529660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000499
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