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Neutrophil–Endothelial Interactions Mediate Angiopoietin-2–Associated Pulmonary Endothelial Cell Dysfunction in Indirect Acute Lung Injury in Mice

Unresolved inflammation in the lung is thought to elicit loss of endothelial cell (EC) barrier integrity and impaired lung function. We have shown, in a mouse model of shock/sepsis, that neutrophil interactions with resident pulmonary cells appear central to the pathogenesis of indirect acute lung i...

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Bibliografische gegevens
Hoofdauteurs: Lomas-Neira, Joanne, Venet, Fabienne, Chung, Chun-Shiang, Thakkar, Rajan, Heffernan, Daithi, Ayala, Alfred
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Thoracic Society 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930935/
https://ncbi.nlm.nih.gov/pubmed/23980650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0148OC
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