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Neutrophil–Endothelial Interactions Mediate Angiopoietin-2–Associated Pulmonary Endothelial Cell Dysfunction in Indirect Acute Lung Injury in Mice

Unresolved inflammation in the lung is thought to elicit loss of endothelial cell (EC) barrier integrity and impaired lung function. We have shown, in a mouse model of shock/sepsis, that neutrophil interactions with resident pulmonary cells appear central to the pathogenesis of indirect acute lung i...

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Detalhes bibliográficos
Main Authors: Lomas-Neira, Joanne, Venet, Fabienne, Chung, Chun-Shiang, Thakkar, Rajan, Heffernan, Daithi, Ayala, Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930935/
https://ncbi.nlm.nih.gov/pubmed/23980650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0148OC
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