The Cytoplasmic Domain of the Integrin α9 Subunit Requires the Adaptor Protein Paxillin to Inhibit Cell Spreading but Promotes Cell Migration in a Paxillin-independent Manner

The integrin α9 subunit forms a single heterodimer, α9β1. The α9 subunit is most closely related to the α4 subunit, and like α4 integrins, α9β1 plays an important role in leukocyte migration. The α4 cytoplasmic domain preferentially enhances cell migration and inhibits cell spreading, effects that d...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Young, Bradford A., Taooka, Yasuyuki, Liu, Shouchun, Askins, Karen J., Yokosaki, Yasuyuki, Thomas, Sheila M., Sheppard, Dean
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60168/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11598204/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.12.10.3214
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!