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Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca(2+) sensitization
Reactive oxygen species play a key role in vascular disease, pulmonary hypertension, and hypoxic pulmonary vasoconstriction. We investigated contractile responses, intracellular Ca(2+) ([Ca(2+)](i)), Rho-kinase translocation, and phosphorylation of the regulatory subunit of myosin phosphatase (MYPT-...
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| Veröffentlicht in: | Free Radic Biol Med |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016743/ https://ncbi.nlm.nih.gov/pubmed/19103285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.11.015 |
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