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PF‐06526290 can both enhance and inhibit conduction through voltage‐gated sodium channels
BACKGROUND AND PURPOSE: Pharmacological agents that either inhibit or enhance flux of ions through voltage‐gated sodium (Na(v)) channels may provide opportunities for treatment of human health disorders. During studies to characterize agents that modulate Na(v)1.3 function, we identified a compound...
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| Yayımlandı: | Br J Pharmacol |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016627/ https://ncbi.nlm.nih.gov/pubmed/29791744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14338 |
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