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PF‐06526290 can both enhance and inhibit conduction through voltage‐gated sodium channels
BACKGROUND AND PURPOSE: Pharmacological agents that either inhibit or enhance flux of ions through voltage‐gated sodium (Na(v)) channels may provide opportunities for treatment of human health disorders. During studies to characterize agents that modulate Na(v)1.3 function, we identified a compound...
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| Published in: | Br J Pharmacol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
John Wiley and Sons Inc.
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016627/ https://ncbi.nlm.nih.gov/pubmed/29791744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14338 |
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