CFTR/ENaC-dependent regulation of membrane potential during human sperm capacitation is initiated by bicarbonate uptake through NBC

To fertilize an egg, sperm must reside in the female reproductive tract to undergo several maturational changes that are collectively referred to as capacitation. From a molecular point of view, the HCO(3)(−)-dependent activation of the atypical soluble adenylyl cyclase (ADCY10) is one of the first...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Puga Molina, Lis C., Pinto, Nicolás A., Torres, Nicolás I., González-Cota, Ana L., Luque, Guillermina M., Balestrini, Paula A., Romarowski, Ana, Krapf, Dario, Santi, Celia M., Treviño, Claudia L., Darszon, Alberto, Buffone, Mariano G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2018
Θέματα:
Signal Transduction
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016479/
https://ncbi.nlm.nih.gov/pubmed/29743243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003166
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