Essential role of CFTR in PKA-dependent phosphorylation, alkalinization and hyperpolarization during human sperm capacitation

Mammalian sperm require to spend a limited period of time in the female reproductive tract to become competent to fertilize in a process called capacitation. It is well established that HCO(3)(−) is essential for capacitation because it activates the atypical soluble adenylate cyclase ADCY10 leading...

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Pubblicato in:J Cell Physiol
Autori principali: Puga Molina, Lis C., Pinto, Nicolás A., Rodríguez, Paulina Torres, Romarowski, Ana, Sanchez, Alberto Vicens, Visconti, Pablo E., Darszon, Alberto, Treviño, Claudia L., Buffone, Mariano G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548537/
https://ncbi.nlm.nih.gov/pubmed/27714810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25634
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