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CFTR/ENaC-dependent regulation of membrane potential during human sperm capacitation is initiated by bicarbonate uptake through NBC
To fertilize an egg, sperm must reside in the female reproductive tract to undergo several maturational changes that are collectively referred to as capacitation. From a molecular point of view, the HCO(3)(−)-dependent activation of the atypical soluble adenylyl cyclase (ADCY10) is one of the first...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6016479/ https://ncbi.nlm.nih.gov/pubmed/29743243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003166 |
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