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Activation of Sonic Hedgehog Signaling Is Associated with Human Osteosarcoma Cells Radioresistance Characterized by Increased Proliferation, Migration, and Invasion

BACKGROUND: Radioresistance restricts the application of radiotherapy in human osteosarcoma (OS). This study investigated the molecular mechanism of radioresistance in OS, which may provide clues to finding ideal targets for genetic therapy. MATERILA/METHODS: The human OS cell line MG63 was employed...

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Vydáno v:Med Sci Monit
Hlavní autoři: Qu, Wei, Li, Dichen, Wang, Yufei, Wu, Qining, Hao, Dingjun
Médium: Artigo
Jazyk:Inglês
Vydáno: International Scientific Literature, Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016436/
https://ncbi.nlm.nih.gov/pubmed/29864766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.908278
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