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Activation of Sonic Hedgehog Signaling Is Associated with Human Osteosarcoma Cells Radioresistance Characterized by Increased Proliferation, Migration, and Invasion

BACKGROUND: Radioresistance restricts the application of radiotherapy in human osteosarcoma (OS). This study investigated the molecular mechanism of radioresistance in OS, which may provide clues to finding ideal targets for genetic therapy. MATERILA/METHODS: The human OS cell line MG63 was employed...

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Détails bibliographiques
Publié dans:Med Sci Monit
Auteurs principaux: Qu, Wei, Li, Dichen, Wang, Yufei, Wu, Qining, Hao, Dingjun
Format: Artigo
Langue:Inglês
Publié: International Scientific Literature, Inc. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6016436/
https://ncbi.nlm.nih.gov/pubmed/29864766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.908278
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