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Emodin Impairs Radioresistance of Human Osteosarcoma Cells by Suppressing Sonic Hedgehog Signaling

BACKGROUND: This study aimed to investigate the possible involvement of sonic hedgehog (Shh) signaling in the radioresistance of human osteosarcoma cells and the inhibitory effects of emodin on radioresistance. MATERIAL/METHODS: Human osteosarcoma (OS) cell line MG63 was employed as parent cells. Af...

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Détails bibliographiques
Publié dans:Med Sci Monit
Auteurs principaux: Qu, Wei, Wang, Yufei, Wu, Qining, Hao, Dingjun, Li, Dichen
Format: Artigo
Langue:Inglês
Publié: International Scientific Literature, Inc. 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719725/
https://ncbi.nlm.nih.gov/pubmed/29203762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.907453
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