Nasal administration of osteopontin peptide mimetics confers neuroprotection in stroke

Osteopontin (OPN), a large secreted glycoprotein with an arginine, glycine, aspartate (RGD) motif, can bind and signal through cellular integrin receptors. We have shown previously that OPN enhances neuronal survival in the setting of ischemia. Here, we sought to increase the neuroprotective potency...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Cereb Blood Flow Metab
Egile Nagusiak: Doyle, Kristian P, Yang, Tao, Lessov, Nikola S, Ciesielski, Thomas M, Stevens, Susan L, Simon, Roger P, King, Jeffrey S, Stenzel-Poore, Mary P
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015748/
https://ncbi.nlm.nih.gov/pubmed/18364727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.17
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