Nasal administration of osteopontin peptide mimetics confers neuroprotection in stroke

Osteopontin (OPN), a large secreted glycoprotein with an arginine, glycine, aspartate (RGD) motif, can bind and signal through cellular integrin receptors. We have shown previously that OPN enhances neuronal survival in the setting of ischemia. Here, we sought to increase the neuroprotective potency...

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Foilsithe in:J Cereb Blood Flow Metab
Main Authors: Doyle, Kristian P, Yang, Tao, Lessov, Nikola S, Ciesielski, Thomas M, Stevens, Susan L, Simon, Roger P, King, Jeffrey S, Stenzel-Poore, Mary P
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015748/
https://ncbi.nlm.nih.gov/pubmed/18364727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.17
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