Nasal administration of osteopontin peptide mimetics confers neuroprotection in stroke

Osteopontin (OPN), a large secreted glycoprotein with an arginine, glycine, aspartate (RGD) motif, can bind and signal through cellular integrin receptors. We have shown previously that OPN enhances neuronal survival in the setting of ischemia. Here, we sought to increase the neuroprotective potency...

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Bibliografske podrobnosti
izdano v:J Cereb Blood Flow Metab
Main Authors: Doyle, Kristian P, Yang, Tao, Lessov, Nikola S, Ciesielski, Thomas M, Stevens, Susan L, Simon, Roger P, King, Jeffrey S, Stenzel-Poore, Mary P
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015748/
https://ncbi.nlm.nih.gov/pubmed/18364727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.17
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