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Impact of RNA polymerase I inhibitor CX-5461 on viral kinase-dependent and -independent cytomegalovirus replication

Human cytomegalovirus (HCMV) infections cause congenital birth defects and disease in immunosuppressed individuals. Antiviral compounds can control infection yet their use is restricted due to concerns of toxicity and the emergence of drug resistant strains. We have evaluated the impact of an RNA Po...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Westdorp, Kristen N., Terhune, Scott S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015744/
https://ncbi.nlm.nih.gov/pubmed/29458130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.02.014
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