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Inhibition of cellular STAT3 synergizes with the cytomegalovirus kinase inhibitor maribavir to disrupt infection

Therapeutic strategies controlling human cytomegalovirus (hCMV) infection are limited due to adverse side effects and emergence of antiviral resistance variants. A compound being evaluated for treating hCMV disease is maribavir (MBV) which disrupts replication by inhibiting the viral kinase pUL97. P...

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Hlavní autoři: Reitsma, Justin M., Terhune, Scott S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845884/
https://ncbi.nlm.nih.gov/pubmed/24070820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2013.09.011
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