Human Cytomegalovirus pUL97 Regulates the Viral Major Immediate Early Promoter by Phosphorylation-Mediated Disruption of Histone Deacetylase 1 Binding

Human cytomegalovirus (HCMV) is a common agent of congenital infection and causes severe disease in immunocompromised patients. Current approved therapies focus on inhibiting viral DNA replication. The HCMV kinase pUL97 contributes to multiple stages of viral infection including DNA replication, con...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bigley, Tarin M., Reitsma, Justin M., Mirza, Shama P., Terhune, Scott S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700266/
https://ncbi.nlm.nih.gov/pubmed/23616659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02825-12
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados