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Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration

Selective neuronal loss is the hallmark of neurodegenerative diseases. In patients with amyotrophic lateral sclerosis (ALS), most motor neurons die but those innervating extraocular, pelvic sphincter and slow limb muscles exhibit selective resistance. We identified 18 genes that show >10-fold dif...

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Dades bibliogràfiques
Publicat a:Neuron
Autors principals: Kaplan, Artem, Spiller, Krista J., Towne, Christopher, Kanning, Kevin C., Choe, Ginn T., Geber, Adam, Akay, Turgay, Aebischer, Patrick, Henderson, Christopher E.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015650/
https://ncbi.nlm.nih.gov/pubmed/24462097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.12.009
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