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Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration

Selective neuronal loss is the hallmark of neurodegenerative diseases. In patients with amyotrophic lateral sclerosis (ALS), most motor neurons die but those innervating extraocular, pelvic sphincter and slow limb muscles exhibit selective resistance. We identified 18 genes that show >10-fold dif...

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Détails bibliographiques
Publié dans:Neuron
Auteurs principaux: Kaplan, Artem, Spiller, Krista J., Towne, Christopher, Kanning, Kevin C., Choe, Ginn T., Geber, Adam, Akay, Turgay, Aebischer, Patrick, Henderson, Christopher E.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015650/
https://ncbi.nlm.nih.gov/pubmed/24462097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.12.009
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