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Matrix Metalloproteinase-9 regulates neuronal circuit development and excitability

In early postnatal development, naturally occurring cell death, dendritic outgrowth and synaptogenesis sculpt neuronal ensembles into functional neuronal circuits. Here we demonstrate that deletion of the extracellular proteinase MMP-9 affects each of these processes, resulting in maladapted neurona...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Murase, Sachiko, Lantz, Crystal, Kim, Eunyoung, Gupta, Nitin, Higgins, Richard, Stopfer, Mark, Hoffman, Dax A., Quinlan, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686372/
https://ncbi.nlm.nih.gov/pubmed/26093382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9295-y
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