Matrix Metalloproteinase-9 regulates neuronal circuit development and excitability

In early postnatal development, naturally occurring cell death, dendritic outgrowth and synaptogenesis sculpt neuronal ensembles into functional neuronal circuits. Here we demonstrate that deletion of the extracellular proteinase MMP-9 affects each of these processes, resulting in maladapted neurona...

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Bibliographic Details
Published in:Mol Neurobiol
Main Authors: Murase, Sachiko, Lantz, Crystal, Kim, Eunyoung, Gupta, Nitin, Higgins, Richard, Stopfer, Mark, Hoffman, Dax A., Quinlan, Elizabeth M.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686372/
https://ncbi.nlm.nih.gov/pubmed/26093382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9295-y
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