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Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration

Selective neuronal loss is the hallmark of neurodegenerative diseases. In patients with amyotrophic lateral sclerosis (ALS), most motor neurons die but those innervating extraocular, pelvic sphincter and slow limb muscles exhibit selective resistance. We identified 18 genes that show >10-fold dif...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Kaplan, Artem, Spiller, Krista J., Towne, Christopher, Kanning, Kevin C., Choe, Ginn T., Geber, Adam, Akay, Turgay, Aebischer, Patrick, Henderson, Christopher E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015650/
https://ncbi.nlm.nih.gov/pubmed/24462097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.12.009
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