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Reduction of Matrix Metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice
Therapeutic strategies are needed for the treatment of amyotrophic lateral sclerosis (ALS). One potential target is matrix metalloproteinase-9 (MMP-9), which is expressed only by fast motor neurons (MNs) that are selectively vulnerable to various ALS-relevant triggers. Previous studies have shown th...
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| Udgivet i: | Neurobiol Dis |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7053168/ https://ncbi.nlm.nih.gov/pubmed/30458231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2018.11.013 |
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