Early and progressive dysfunction revealed by in vivo neurite imaging in the rNLS8 TDP-43 mouse model of ALS
Amyotrophic lateral sclerosis (ALS) is characterized by transactive response DNA-binding protein 43 (TDP-43) pathology, progressive loss of motor neurons and muscle dysfunction. Symptom onset can be insidious and diagnosis challenging. Conventional neuroimaging is used to exclude ALS mimics, however...
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Autors principals: | , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Elsevier
2022-01-01
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Col·lecció: | NeuroImage: Clinical |
Matèries: | |
Accés en línia: | http://www.sciencedirect.com/science/article/pii/S221315822200081X |
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