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Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx
BACKGROUND: In hepatocyte nuclei, hepatitis B virus (HBV) genomes occur episomally as covalently closed circular DNA (cccDNA). The HBV X protein (HBx) is required to initiate and maintain HBV replication. The functional nuclear localization of cccDNA and HBx remains unexplored. RESULTS: To identify...
Tallennettuna:
| Julkaisussa: | Epigenetics Chromatin |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6015472/ https://ncbi.nlm.nih.gov/pubmed/29933745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0204-2 |
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