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Concept of DNA Lesion Longevity and Chromosomal Translocations
A subset of chromosomal translocations related to B cell malignancy in human patients arise due to DNA breaks occurring within defined 20 to 600 basepair zones. Several factors influence the breakage rate at these sites including transcription, DNA sequence, and topological tension. These factors fa...
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| Publicado en: | Trends Biochem Sci |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6014902/ https://ncbi.nlm.nih.gov/pubmed/29735400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.04.004 |
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