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Dissecting the Roles of Divergent and Convergent Transcription in Chromosome Instability

The interplay of transcription, topological tension and chromosome breakage is a subject of intense interest, but, with so many facets to the problem, difficult to test. Here, we vary the orientation of promoters relative to one another in a yeast system that permits sensitive detection of chromosom...

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Detalles Bibliográficos
Publicado en:Cell Rep
Autores principales: Pannunzio, Nicholas R., Lieber, Michael R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028021/
https://ncbi.nlm.nih.gov/pubmed/26804908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.098
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