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Concept of DNA Lesion Longevity and Chromosomal Translocations
A subset of chromosomal translocations related to B cell malignancy in human patients arise due to DNA breaks occurring within defined 20 to 600 basepair zones. Several factors influence the breakage rate at these sites including transcription, DNA sequence, and topological tension. These factors fa...
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| Publicado no: | Trends Biochem Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6014902/ https://ncbi.nlm.nih.gov/pubmed/29735400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2018.04.004 |
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