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Sequential actions of phosphatidylinositol phosphates regulate phagosome-lysosome fusion

Phagosomes mature into phagolysosomes by sequential fusion with early endosomes, late endosomes, and lysosomes. Phagosome-with-lysosome fusion (PLF) results in the delivery of lysosomal hydrolases into phagosomes and in digestion of the cargo. The machinery that drives PLF has been little investigat...

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Publicat a:Mol Biol Cell
Autors principals: Jeschke, Andreas, Haas, Albert
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014173/
https://ncbi.nlm.nih.gov/pubmed/29237821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-07-0464
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