Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis

Professional phagocytic cells ingest microbial intruders by engulfing them into phagosomes, which subsequently mature into microbicidal phagolysosomes. Phagosome maturation requires sequential fusion of the phagosome with early endosomes, late endosomes, and lysosomes. Although various phosphoinosit...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Jeschke, Andreas, Zehethofer, Nicole, Lindner, Buko, Krupp, Jessica, Schwudke, Dominik, Haneburger, Ina, Jovic, Marko, Backer, Jonathan M., Balla, Tamas, Hilbi, Hubert, Haas, Albert
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403170/
https://ncbi.nlm.nih.gov/pubmed/25825728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423456112
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