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Understanding phosphatidylinositol-3-phosphate dynamics during autophagosome biogenesis

Autophagosomes, the hallmark of autophagy, are double-membrane vesicles sequestering cytoplasmic components. They are generated at the phagophore assembly site (PAS), the phagophore being the precursor structure of these carriers. According to the current model, autophagosomes result from the elonga...

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Hlavní autoři: Cebollero, Eduardo, van der Vaart, Aniek, Reggiori, Fulvio
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541308/
https://ncbi.nlm.nih.gov/pubmed/22992453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22162
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