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Understanding phosphatidylinositol-3-phosphate dynamics during autophagosome biogenesis

Autophagosomes, the hallmark of autophagy, are double-membrane vesicles sequestering cytoplasmic components. They are generated at the phagophore assembly site (PAS), the phagophore being the precursor structure of these carriers. According to the current model, autophagosomes result from the elonga...

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Detalhes bibliográficos
Main Authors: Cebollero, Eduardo, van der Vaart, Aniek, Reggiori, Fulvio
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541308/
https://ncbi.nlm.nih.gov/pubmed/22992453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22162
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