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Understanding phosphatidylinositol-3-phosphate dynamics during autophagosome biogenesis

Autophagosomes, the hallmark of autophagy, are double-membrane vesicles sequestering cytoplasmic components. They are generated at the phagophore assembly site (PAS), the phagophore being the precursor structure of these carriers. According to the current model, autophagosomes result from the elonga...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cebollero, Eduardo, van der Vaart, Aniek, Reggiori, Fulvio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541308/
https://ncbi.nlm.nih.gov/pubmed/22992453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22162
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