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Understanding phosphatidylinositol-3-phosphate dynamics during autophagosome biogenesis

Autophagosomes, the hallmark of autophagy, are double-membrane vesicles sequestering cytoplasmic components. They are generated at the phagophore assembly site (PAS), the phagophore being the precursor structure of these carriers. According to the current model, autophagosomes result from the elonga...

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Détails bibliographiques
Auteurs principaux: Cebollero, Eduardo, van der Vaart, Aniek, Reggiori, Fulvio
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541308/
https://ncbi.nlm.nih.gov/pubmed/22992453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.22162
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