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Phosphatidylinositol-3-Phosphate Clearance Plays a Key Role in Autophagosome Completion

BACKGROUND: The biogenesis of autophagosomes, the hallmark of autophagy, depends on the function of the autophagy-related (Atg) proteins and the generation of phosphatidylinositol-3-phosphate (PtdIns3P) at the phagophore assembly site (PAS), the location where autophagosomes arise. The current model...

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Autors principals: Cebollero, Eduardo, van der Vaart, Aniek, Zhao, Mantong, Rieter, Ester, Klionsky, Daniel J., Helms, J. Bernd, Reggiori, Fulvio
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615650/
https://ncbi.nlm.nih.gov/pubmed/22771041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.06.029
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