Chargement en cours...
On the prevalence of bridged macrocyclic pyrroloindolines formed in regiodivergent alkylations of tryptophan
A Friedel–Crafts alkylation is described that efficiently transforms tryptophan-containing peptides into macrocycles of varying ring connectivity. Factors are surveyed that influence the distribution of regioisomers, with a focus on indole C3-alkylations leading to bridged endo-pyrroloindolines. We...
Enregistré dans:
| Publié dans: | Chem Sci |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Royal Society of Chemistry
2016
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6014094/ https://ncbi.nlm.nih.gov/pubmed/30155060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc04612b |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|