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Template-induced macrocycle diversity through large ring-forming alkylations of tryptophan

Macrocyclic peptidomimetics are valuable in research and serve as lead compounds in drug discovery efforts. New methods to prepare such structures are of considerable interest. In this pilot study, we show that an organic template harboring a latent cinnamyl cation participates in novel Friedel-Craf...

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Detalhes bibliográficos
Main Authors: Lawson, Kenneth V., Rose, Tristan E., Harran, Patrick G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746997/
https://ncbi.nlm.nih.gov/pubmed/23976797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2013.05.060
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