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Template-constrained macrocyclic peptides prepared from native, unprotected precursors

Peptide–protein interactions are important mediators of cellular-signaling events. Consensus binding motifs (also known as short linear motifs) within these contacts underpin molecular recognition, yet have poor pharmacological properties as discrete species. Here, we present methods to transform in...

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Detalhes bibliográficos
Main Authors: Lawson, Kenneth V., Rose, Tristan E., Harran, Patrick G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791740/
https://ncbi.nlm.nih.gov/pubmed/24043790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311706110
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