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Synthesis of a Large Library of Macrocyclic Peptides Containing Multiple and Diverse N-alkylated Residues

Large combinatorial libraries of macrocyclic peptides are a useful source of bioactive compounds. However, peptides are not generally cell permeable, so there is great interest in the development of methods to create large libraries of modified peptides. In particular, N-alkylation of peptides is kn...

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Dettagli Bibliografici
Pubblicato in:Mol Biosyst
Autori principali: Morimoto, Jumpei, Kodadek, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573835/
https://ncbi.nlm.nih.gov/pubmed/26067000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5mb00308c
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