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Synthesis of a Large Library of Macrocyclic Peptides Containing Multiple and Diverse N-alkylated Residues

Large combinatorial libraries of macrocyclic peptides are a useful source of bioactive compounds. However, peptides are not generally cell permeable, so there is great interest in the development of methods to create large libraries of modified peptides. In particular, N-alkylation of peptides is kn...

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Detalhes bibliográficos
Publicado no:Mol Biosyst
Main Authors: Morimoto, Jumpei, Kodadek, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573835/
https://ncbi.nlm.nih.gov/pubmed/26067000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5mb00308c
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