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Synthesis of a Large Library of Macrocyclic Peptides Containing Multiple and Diverse N-alkylated Residues

Large combinatorial libraries of macrocyclic peptides are a useful source of bioactive compounds. However, peptides are not generally cell permeable, so there is great interest in the development of methods to create large libraries of modified peptides. In particular, N-alkylation of peptides is kn...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biosyst
Hauptverfasser: Morimoto, Jumpei, Kodadek, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573835/
https://ncbi.nlm.nih.gov/pubmed/26067000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5mb00308c
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