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Cell Permeable Peptides Containing “Cycloalanine” Residues
We present here an efficient alternative to the N-methylation for the purpose of morphing protein-binding peptides into more serum stable and cell permeable compounds. This involves the incorporation of a ”cycloalanine (CyAla)” into a peptide in a way that avoids difficult coupling steps. We demonst...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5220248/ https://ncbi.nlm.nih.gov/pubmed/27529332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201605745 |
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