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High-Throughput Evaluation of Relative Cell Permeability between Peptoids and Peptides

Peptides are limited in their use as drugs due to low cell permeability and vulnerability to proteases. In contrast, peptoids are immune to enzymatic degradation and some peptoids have been shown to be relatively cell permeable. In order to facilitate future design of peptoid libraries for screening...

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Bibliographic Details
Main Authors: Tan, Niclas C., Yu, Peng, Kwon, Yong-Uk, Kodadek, Thomas
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490712/
https://ncbi.nlm.nih.gov/pubmed/18490170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.04.074
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