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Targeting HIV Transcription: The Quest for a Functional Cure
Antiretroviral therapy (ART) potently suppresses HIV-1 replication, but the virus persists in quiescent infected CD4(+)T cells as a latent integrated provirus, and patients must indefinitely remain on therapy. If ART is terminated, these integrated proviruses can reactivate, driving new rounds of in...
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| Udgivet i: | Curr Top Microbiol Immunol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4409574/ https://ncbi.nlm.nih.gov/pubmed/25731772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2015_435 |
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