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Targeting HIV Transcription: The Quest for a Functional Cure

Antiretroviral therapy (ART) potently suppresses HIV-1 replication, but the virus persists in quiescent infected CD4(+)T cells as a latent integrated provirus, and patients must indefinitely remain on therapy. If ART is terminated, these integrated proviruses can reactivate, driving new rounds of in...

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Bibliografische gegevens
Gepubliceerd in:Curr Top Microbiol Immunol
Hoofdauteurs: Mousseau, Guillaume, Mediouni, Sonia, Valente, Susana T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4409574/
https://ncbi.nlm.nih.gov/pubmed/25731772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2015_435
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