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Role of Host Factors on the Regulation of Tat-Mediated HIV-1 Transcription

BACKGROUND: The viral transactivator Tat protein is a key modulator of HIV-1 replication, as it regulates transcriptional elongation from the integrated proviral genome. Tat recruits the human transcription elongation factor b, and other host proteins, such as the super elongation complex, to activa...

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Bibliographic Details
Published in:Curr Pharm Des
Main Authors: Mousseau, Guillaume, Valente, Susana T.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5731639/
https://ncbi.nlm.nih.gov/pubmed/28641539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1381612823666170622104355
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