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Strategies to Block HIV Transcription: Focus on Small Molecule Tat Inhibitors

After entry into the target cell, the human immunodeficiency virus type I (HIV) integrates into the host genome and becomes a proviral eukaryotic transcriptional unit. Transcriptional regulation of provirus gene expression is critical for HIV replication. Basal transcription from the integrated HIV...

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Detalhes bibliográficos
Main Authors: Mousseau, Guillaume, Valente, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009808/
https://ncbi.nlm.nih.gov/pubmed/24832514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology1030668
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