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The Novel Pathogenesis of Retinopathy Mediated by Multiple RTK Signals is Uncovered in Newly Developed Mouse Model

Pericyte desorption from retinal blood vessels and subsequent vascular abnormalities are the pathogenesis of diabetic retinopathy (DR). Although the involvement of abnormal signals including platelet-derived growth factor receptor-β (PDGFRβ) and vascular endothelial growth factor-A (VEGF-A) have bee...

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Enregistré dans:
Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Kitahara, Hideyuki, Kajikawa, Sayaka, Ishii, Yoko, Yamamoto, Seiji, Hamashima, Takeru, Azuma, Erika, Sato, Hikari, Matsushima, Takako, Shibuya, Masabumi, Shimada, Yutaka, Sasahara, Masakiyo
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6013936/
https://ncbi.nlm.nih.gov/pubmed/29724654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.04.021
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